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Is there a risk of severe radiation toxicity for a patient with paraneoplastic dermatomyositis due to lung cancer?

For a Stage III NSCLC looking to do definitive chemoRT who required IVIG and high-dose prednisone for paraneoplastic myopathy (mimicking dermatomyositis), how would you counsel the patient on RT risks? Are the risks similar to connective vascular disease/CVD?
1 Answer
Mednet Member
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

One of the treatments for paraneoplastic dermatomyositis is treatment of underlying malignancy which can lead to remission of dermatomyositis in some.

I would treat with definitive intent with RT and a few pts I have treated have had improvement of their symptoms with regression of cancer

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