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Is there a role for a post-operative boost in a patient with rectal cancer who has a positive margin after total neoadjuvant chemo and chemoradiation therapy?

Total neoadjuvant therapy consisted of with FOLFOX and chemoradiation therapy with Xeloda and 50.4 Gy. Would you deliver a boost to the area and if so, to what dose?
1 Answer
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Radiation Oncology · University of North Carolina at Chapel Hill
Answered on

As is usually the case with questions of this sort there is not just a yes or no answer. First, we rarely use a postop boost as if we have concerns about the circumferential margin on our initial evaluation, we set up the patient for intraoperative RT. IORT has big advantages in giving a very high l...

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