Is there a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients?

There is no good-quality evidence supporting a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients. The efficacy of nitazoxanide in viral gastroenteritis is supported by a small manufacturer-sponsored randomized, double-blind trial in non-immunocompromised ...

https://www.sciencedirect.com/science/article/abs/pii/S160061352600198X

Conclusion: Although safe, NTZ likely contributes little to the management of chronic NoV.