Is there an effective treatment for severe radiation fibrosis of the skin after radiotherapy to the breast or other areas?  

I have heard of long term pentoxifylline and Vitamin E daily combination that can prevent and even reverse radiation fibrosis (Delanian et al. JCO 2005). How effective is this and is this used commonly in practice? Any topical agents that are helpful?



Answer from: Radiation Oncologist at Community Practice

Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Academic Institution