Is there any contraindication to concurrent administration of radioactive iodine in a patient on immunotherapy?

Hello, unfortunately it is not known whether RAI can be given safely with nivolumab for treatment of PTC. Though I don't know of any absolute contraindications. Most of the studies using anti PD1 antibodies for metastatic thyroid carcinoma are in the RAI refractory populations. There are reports of using RAI to treat anti PD1 associated thyroiditis without an increase in toxicity, so I think it would be reasonable to proceed with both cautiously, and with the patient understanding the uncertaint...