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Is there any data to support SLNB instead of ALND in patients with clinically N2-3 breast cancer after neoadjuvant chemotherapy?

Alliance Z-1071 cohort had 5% with cN2 and <1% fixed or matted and the current Alliance trial 011202 only allows cN1. ALND has never been shown to improve survival.
1 Answer
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

The sentina trial and acsog trial had Predominant N1 disease and negative predictive value Of SNLN is not known for N2 or N3 disease

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