Would you consider 5-fraction whole breast RT for a patient with multiple positive margins following lumpectomy for whom reexcision is not possible?
If so, would you boost sequentially or with an SIB? If not, would you consider endocrine therapy alone?
Answer from: Radiation Oncologist at Community Practice
It’s not the whole-breast fractionation that matters, as 5 or 15 fractions are adequate doses for whole breast, but I would definitely add a boost equivalent to a dose of 16 Gy to the surgical bed.