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Topics:
Rheumatology
•
Infectious Disease
Is there any evidence that TNF inhibitors alter immunogenicity of vaccines?
If so, does delaying/skipping a dose improve immunogenicity?
Related Questions
What are your vaccine recommendations while patients are on biologics?
Do you recommend chronic oral suppressive antibiotics after initial intensive treatment of 6-8 weeks in patients with culture-negative prosthetic joint or bone infections with retained hardware?
In a patient with a history of seropositive erosive RA who has undergone treatment for a periprosthetic joint infection and currently has an antibiotic spacer in place with clinical improvement, what is the appropriate timing and strategy for restarting DMARDs and/or biologic therapy to balance infection risk with RA disease control?
How would you manage a patient with progressive/refractory molluscum contagiosum who is well controlled on methotrexate for seropositive rheumatoid arthritis?
Do you provide empiric doxycycline for Lyme Disease to asymptomatic patients after a tick bite who haven't developed Erythema migrans or are not sure it was an Ixodes tick?
Should patients starting cyclophosphamide be screened routinely for latent tuberculosis (TB)?
What is the interpretation of an IGRA with positive TB wells and negative nil and negative mitogen wells?
How would you treat an asymptomatic patient with a positive Blastomyces antibody, evidence of prior granulomatous lung disease on imaging, and who may require immunosuppression in the future?
In light of recent measles outbreaks, have you adjusted your vaccination counseling or preventive strategies for adult immunocompromised patients?
What is the recommended fungal workup in an immunocompromised patient after 5 days of persistent fever?