Is there any role for adjusting how long to hold anticoagulation perioperatively based on DOAC dose?
For example, if on a prophylactic dose of DOAC, planned for an upcoming procedure such as colonoscopy or cystoscopy, would you hold for 24 hours prior to the procedure rather than the typical 48 hours?
1 Answer
Mednet MemberInvited Expert
Hematology · Mayo Clinic
Answered on
The PAUSE trial evaluated perioperative management of DOACs. However, only 20% and 16% of patients were on prophylactic doses of apixaban and rivaroxaban, respectively. It was suggested to hold the drugs for two days, and one day before high-risk and low-risk procedures. A useful review of this appr...
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