Is there any way to safely treat patients with mCRPC with 177-Lu PSMA who are on hemodialysis?

For the most part, no. Not unless you're a big academic medical center with a robust multidisciplinary team willing to tackle the significant logistical challenges associated with this scenario.

I'm aware of no literature in this scenario specifically for Pluvicto, but we can look at the radiopharmac...

In appropriately selected patients, Pluvicto can be administered well when on dialysis.

In our center (large community hospital), I coordinate with nephrology and the dialysis team to perform dialysis in a separate room. We collect the dialysis tubing and decay the radiation in nuclear medicine. We ...