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Knowing that spread of lobular carcinoma is often more insidious than ductal carcinoma, do you order different staging studies for lobular cancer?

For example, would you order a PET/CT to evaluate for lymphatic or distant metastatic disease?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · University of Washington Department of Medicine
Answered on

No I would not stage lobular cancers differently than other histologies. There is no clear evidence that node negative lobular carcinomas are more likely to have distant metastases at initial diagnosis than other histologies. Moreover, lobular cancers are notoriously difficult to detect by imaging. ...

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