Blood Adv 2020 Jan 28
American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support.
Related Questions
What are your target goals during transfusion, either prophylactically or during acute complication? Does your management change between vaginal deliv...
New comment by at UT Southwestern Medical Center ( May 17, 2021)
Thank you for this very informative answer, and for the references!
e.g. K, Fya, s, etc
New answer by at New York Blood Center (May 12, 2022)
Patients who develop antibodies to minor RBC antigens have shown themselves to be antibody responders and should receive limited matched red cells for Abs to C/c, E/e, and K a...
New comment by at Rush University Medical Center ( April 18, 2023)
Agree with the excellent answer by my colleague. One time red cell exchange in patients has not been shown to significantly improve pain crisis.
Chronic red cell exchange can...
How do you decide between simple transfusion and red cell exchange?While the 2020 ASH Guidelines provide some conditional guidance on transfusion supp...
New answer by at University of Iowa Hospitals and Clinics (July 31, 2025)
Unfortunately, I am not aware of a more comprehensive document than the ASH guidelines. These are what I use to define my default management strategy, often in coordination wi...