Radiother Oncol 2018 May
Once-weekly versus every-other-day stereotactic body radiotherapy in patients with prostate cancer (PATRIOT): A phase 2 randomized trial.
Related Questions
Given the PATRIOT trial and hypo-FLAME 2.0, do you consider once-a-week prostate SBRT instead of every other day?
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1 Answers
Mednet Member
Radiation Oncology · UC San Diego
Yes, it is reasonable to offer weekly prostate SBRT to patients.Quick review of evidence: hypo-FLAME 2.0 (De Cock et al., PMID 37178932) was a phase II single-arm trial that used 35 Gy/5 fx with FLAME-style isotoxic SIB up to 50 Gy/5 fx to visible tumor(s) with a bi-weekly schedule. N=124 participan...
How would you manage a treatment interruption during SBRT to the liver?
2 Answers
Mednet Member
Radiation Oncology · Mayo Clinic, Rochester
The answer to this question is "it depends". Given that the original delivery of SBRT was two fractions per week over a period of 2.5-3 weeks for 3-5 fractions, if the patient completes SBRT within this time frame, it would still not truly qualify as a treatment interruption.Further, if you deliver ...