Int J Radiat Oncol Biol Phys 2016 Jul 15
Palliative Short-Course Radiation Therapy in Rectal Cancer: A Phase 2 Study.
Related Questions
In a patient with dMMR rectal adenocarcinoma, does the use of palliative RT for bleeding (5 Gy x 5) preclude the use of immunotherapy?
2 Answers
Mednet Member
Medical Oncology · Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty
In dMMR rectal adenocarcinoma, short-course palliative pelvic radiotherapy is the faster, more reliable tool for controlling tumor bleeding than checkpoint inhibitor immunotherapy due to a direct hemostatic effect with bleeding-control rates of roughly 81–100% over days to a few weeks. Immunotherapy...
What is the preferred palliative regimen for elderly patients with rectal cancer who elect to forego surgery?
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3 AnswersMednet Member
Radiation Oncology · Fox Chase Cancer Center
This is a question that comes up somewhat frequently and I don't believe really has a definitive answer. I myself have used multiple regimens in this situation. I think it really depends on the performance status and life expectancy of the particular patient. This is also a topic that may bring out ...