This is a question that comes up somewhat frequently and I don't believe really has a definitive answer. I myself have used multiple regimens in this situation. I think it really depends on the performance status and life expectancy of the particular patient. This is also a topic that may bring out ...

I agree with @Joshua E. Meyer’s points, and I also often favor RT alone to 25 Gy in 5 fractions for the majority of my poor performance status non-surgical elderly rectal cancer patients who may benefit from palliative RT as it is typically safe, brief, and effective. Involving the patient&rsq...

The preferred palliative regimen for elderly patients with rectal cancer who elect to forego surgery depends on various factors such as the patient's overall health, and comorbidities. In general, palliative treatment aims to alleviate symptoms and improve quality of life for the patient. Patients ...