What is your approach to treating nephrotic syndrome with positive PLA2R titers, prior to a kidney biopsy?

According to the 2021 KDIGO guidelines, a positive anti-PLA2R antibody test in a patient with nephrotic syndrome is highly specific (~99%) for primary membranous nephropathy, allowing for diagnosis and treatment without a kidney biopsy unless atypical features—such as a rapidly declining eGFR, concu...