Should inoperable squamous cell carcinoma of the esophagus be treated to doses > 60 Gy?

The article mentioned does not, in my opinion, provide sufficient evidence to justify a change in clinical practice. As a general rule, I think we should be extremely careful about using data from retrospective data reviews, such as this review or the commonly used NCDB database, to assert that one ...

I agree with @Dr. First Last's answer above. I'd also add that a randomized trial of 50 Gy vs. 60 Gy chemoRT for esophageal SCC has recently been reported in abstract form and did not show any benefit to dose escalation. It has generally been our practice at MSKCC to boost SCC above 50.4 Gy if no su...