Should JAK inhibitors and anti-IL6 medications be avoided in patients with known diverticulosis?

The development of diverticulitis, including complications such as bowel perforation, has been reported in patients taking JAK and IL-6 inhibitors (for example, see here and here). As a result, a history of diverticulitis is a relative contraindication for these agents (and carry a “use with caution...

A good and clinically relevant question. I will assume the patient has rheumatoid arthritis, even though I would do the same for others also. We have multiple other options for the treatment of RA, with different modes of action, which as far as my interpretation of the data goes, are similar to one...