Should we be considering transsphenoidal surgical resection as first-line therapy for prolactinomas?

Should transsphenoidal surgical resection be considered as the first-line therapy for prolactinomas?

• Yes, surgery should be considered as first-line therapy for select patients (e.g., young women with microprolactinomas or well-circumscribed macroprolactinomas)
• No, dopamine agonists should remain the first-line treatment for most patients due to their effectiveness and patient tolerance
• Other