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Under what clinical circumstances, if any, would you prescribe fenofibrate along with statin therapy?

2 Answers
Mednet Member
Mednet Member
Endocrinology · Medical University of South Carolina College of Medicine

Yes, I do sometimes combine fibrates and statins. Usually, it’s in the setting of needing to treat severe hypertriglyceridemia with the fibrate in a patient who also has hypercholesterolemia and an indication for a statin. If a patient is on a statin and still has mild to moderate hypertriglyceridem...

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Mednet Member
Mednet Member
Endocrinology · McGill University

I agree with Dr. @Dr. First Last's response.

Additionally, there is evidence that Fenofibrate can reduce retinopathy progression in diabetics, in post hoc evaluation (FIELD trial subanalysis; ACCORD trial subanalysis and in a randomized clinical trial Preiss et al., PMID 38905569).

It is not yet a wel...

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