Under which circumstances is there a role for reduction in immunosuppression post-SOT in a patient with recurrent CMV viremia and/or disease? 

While the decision regarding immunosuppression is always up to the primary transplant team, as the infectious disease consultant, I always inquire about the ability to reduce immunosuppression during episodes of CMV syndrome or disease even if it is a first episode. This becomes even more important ...

Every opportunistic infection is an opportunity to review immunosuppression and optimize it.

Recurrent CMV poses a concurrent risk and needs to be evaluated in certain scenarios and for certain risk factors:

1. Is it in the setting of recent rejection that required escalation of Abx?
2. Does it require a...