What adjuvant chemotherapy regimen is most appropriate for a patient with local recurrence several years after surgery and ddAC-T for localized breast cancer?

In this situation, it is preferable to use a chemotherapy regimen that has been shown to be effective in the adjuvant setting. For a patient who has already received ddAC-T, my choice would be TC (docetaxel/cyclophosphamide), or even CMF. The role of chemotherapy for locoregional recurrence is still...

I agree with @Dr. First Last. The CALOR study supports "physicians choice" chemotherapy in the setting of a local recurrence but unfortunately it doesn't guide specific chemotherapy regimens. My specific chemotherapy recommendations are often influenced by the disease free interval, histology, compl...