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What adjuvant therapy (regimen and duration) would you use for T2N1 ampullary adenocarcinoma (intestinal type)?

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What adjuvant therapy would you offer for node positive ampullary adenocarcinoma?

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1 Answer
Mednet Member
Mednet Member
Medical Oncology · University of Texas MD Anderson Cancer Center
Answered on

Unfortunately, we don't have randomized data to guide adjuvant chemotherapy for ampullary adenocarcinoma. For the intestinal type, I favor CAPOX or FOLFOX for 6 months. For the pancreatobiliary type, I favor modified FOLFIRINOX for 6 months (PS 0-1) or gemcitabine/capecitabine for 6 months (PS 2).

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