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What adjuvant therapy would you recommend for a patient with high grade serous ovarian cancer who has surgically confirmed unresectable disease after a partial response to 6 cycles of a platinum doublet?

2 Answers
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Gynecologic Oncology · City of Hope
Answered on

This decision would depend on several factors; the patient's frailty status, disease spread, molecular signatures, and response thus far. If she continues to respond well to the platinum couplet, my approach would involve adding bevacizumab if it hasn't been administered yet. I might also consider a...

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Mednet Member
Mednet MemberInvited Expert
Gynecologic Oncology · Center of Hope
Answered on

The question posed describes a relatively common scenario. She has platinum-sensitive disease and to date, has had only a partial response to front-line therapy. Her overall prognosis is worse compared with patients who are surgically resectable, regardless of the number of neoadjuvant chemotherapy ...

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