What adjuvant treatment would you recommend for stage III colon cancer in a patient >75yo but with a good performance status?

As is often the case, I'd have to say "it depends". If the patient had stage IIIA disease for which the survival curves are better than IIB and comparable to IIA patients, I'd be inclined to offer capecitabine alone (providing no other poor risk factors such as insufficient nodal count, poorly differentiated histology, angiolymphatic or perineural invasion). If stage IIIB or higher and if limited comorbidities (i.e. low competing cause of death such as cardiac or pulmonary conditions) and lack o...