Good question, but the way it is phrased makes it difficult to answer: Generally, all ASMs can suppress seizure activity and interictal discharges to some degree. There is a huge difference among the subtypes of epilepsy, for example in IGE and LGS, there may be a correlation between the interic...

Both Keppra and Depakote are capable of suppressing spike and wave.

I agree with Dr. @Amin.