When using SIB for HN IMRT there are a few different options for dose levels.  In the definitive setting, I typically use 70/63/56 Gy in 2.0/1.8/1.6 Gy/fraction over 35 fractions.  The 1.6 Gy/fraction is less than ideal, but the small dose escalation to 56 Gy (rather than 50 Gy i...

Concomitant boost IMRT requires just one, while sequential requires two plans (disregarding the possible need for adaptive re-planning, which would be the same in both). BED2 doses to the targets and to specified organs are expected to be similar, however, the doses to the non-defined tissues are hi...

I tend to use Sequential plans for patients receiving radiation alone, as I am somewhat uncomfortable using less than 1.8 Gy daily dose in the absence of chemotherapy.  Sequential plans in general result also in better sparing of structures more than ~1 cm away from the high dose target.  ...