What are the indications for adjuvant radiotherapy for basal cell carcinoma of the skin of the head and neck?
NCCN lists only substantial perineural invasion. What about other high-risk adverse features such as histologic subtype, multiple recurrences, depth of invasion, size, etc.? What is your definition of substantial perineural invasion?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Memorial Sloan Kettering Cancer Center
Answered on
I rarely give adjuvant radiotherapy for resected BCCs because there is little data demonstrating a benefit. For BCCs, with squamous features or nodal metastases, I generally manage as a cSCC. Some reasons to consider adjuvant RT to resected BCC primary tumor might be:
-T3/T4 primary (by AJCC 7)
-R2 resection with no option for additional surgery
-R1 resection with limited options for salvage surgery at time of future local recurrence
PNI in isolation generally is a risk factor for local recurren...
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