What are your thoughts on the results from the AQUATIC trial which showed that the addition of aspirin daily + oral anticoagulation in patients > 6 months from PCI and with high atherothrombotic risk was associated with a higher risk of death, MI, stroke, coronary revascularization and acute limb ischemia, compared to oral anticoagulation alone?

1 Answers

Mednet Member

Cardiology · Lahey Hospital & Medical Center, Burlington

I think AQUATIC is a well-designed definitive trial. It shows that in patients with chronic CAD (at least 6 mo. out from stent) who are also receiving anticoagulation (typically for AFib), the use of anticoag monotherapy is safer (statistically lower risk in terms of a composite endpoint as well as ...