What BED10 do you aim for when prescribing hypofractionated treatment for ultra-central tumors of the lung?

Eg 10-20 fraction regimens. And how (hot spot %, mean, D99) do you prescribe the dosage?

Answer from: Radiation Oncologist at Academic Institution

It depends on how you define "ultra-central." If the tumor is within 1 cm but not touching a more distal bronchus like lobar bronchus, I may still use a prescription dose of 50 Gy in 5 fractions, while limiting hotspots to 120% and allowing some undercoverage of PTV to meet proximal TBT constraints....

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Radiation Oncologist at Mon Health
I understand that there is published data on 72 Gr...

Answer from: Radiation Oncologist at Community Practice

BED10 (3) for the regimens listed above (and a few others) 50 Gy/5 fx: 100 Gy (216.67 Gy) 60 Gy/8 fx: 105 Gy (210 Gy) 70 Gy/10 fx: 119 Gy (233.33 Gy) 62.5 Gy/10 fx: 101.56 Gy (192.71 Gy) 60 Gy/15 fx: 84 Gy (140 Gy) 72 Gy/18 fx: 100.8 Gy (168 Gy) 77 Gy/25 fx: 100.7 Gy (156.05 Gy) 79.5 Gy/30 f...

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What BED10 do you aim for when prescribing hypofractionated treatment for ultra-central tumors of the lung?

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