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What chemotherapy do you use with radiation for urothelial carcinoma with squamous differentiation?

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Mednet Member
Mednet Member
Medical Oncology · University of Washington School of Medicine

In case of primary or dominant urothelial carcinoma with squamous cell features, would approach similar to pure urothelial carcinoma and consider same radio-sensitizing chemo that we are using in S1806 phase III trial. Doses below may not fully reflect S1806 protocol and also depends on the patient ...

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Mednet Member
Mednet Member
Medical Oncology · AdventHealth Cancer Institute

While data for pure non-urothelial histology and trimodality therapy (TMT) are lacking, a retrospective study suggests that variant urothelial carcinoma (VUC, urothelial carcinoma with other histologic components except small-cell) exhibits similar outcomes when compared with pure urothelial carcino...

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