What chemotherapy regimen do you prefer for postmenopausal women with T1 ER positive tumors with 1 positive LN?
Is TC or CMF adequate or is only ddAC -> T recommended?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · University of Pittsburgh School of Medicine
Answered on · Updated on
For T1N1M0 ER positive tumors, I first do a Mammaprint. In MINDACT, Mammaprint low risk ER + N+ (up to three nodes) tumors had no improvement in 5 year DDFS (still about 94-95%) with the addition of chemotherapy to endocrine therapy.
If the woman had a high risk Mammaprint, I would give AC x 4 follow...
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