What chemotherapy regimen would you recommend for high risk ER+/Her2- LN negative breast cancer with high genomic risk disease?

For the patient described, with high genomic risk but otherwise good-risk features (ER positive, HER2 negative, node negative) I would recommend TC x 4 cycles as reported in Jones et al (JCO 2009, 27:1177). The use of anthracycline plus taxane adds benefit overall as shown in the ABC trials, but for...