What chemotherapy would you recommend for a stage IC3 large cell neuroendocrine tumor of the ovary?

The more unusual the disease, the more it is helpful to get more information. First, although not a perfect test, the PET Dotatate may shed more light on prognosis, and thus be helpful in that way. Also, it is not always clear if these are primary or mets from another organ NET. The specialized PET may help in that regard as well. Would also consider performing molecular profiling. This may shed light on general NET options that are not being considered. Since there is no "right answer" here regarding CT vs EP, it is worth a shot. If payer coverage is an issue, would at least get ctDNA assay for the same. It is highly affordable. Ideally, it should be tissue analysis or both, but at least liquid biopsy with ctDNA.