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What concentration/dose of mitomycin C do you use for trabeculectomies and XENs and how do you titrate based on patient factors?

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Mednet Member
Mednet Member
Ophthalmology · UPMC Vision Institute

I use the mitosol kit and reconstitute at 0.2 mg/ml (0.02%). I inject the mitomycin at the end of the case, after ensuring watertight conjunctiva closure by raising a bleb via a corneal paracentesis. My standard dose then is 60 ug injected (0.3ml of 0.2 mg/ml), but I may titrate that dose/volume up ...

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