What criteria do you use to determine the resectability of mucosal melanoma of the H&N region?

Obviously, the best specialist to answer the posted question would be a H&N surgeon. As a Rad Onc enthusiast who conducted a retrospective study about the subject long ago (Lee et al., PMID 8302112), I’ll provide my own 2-cents here:

Mucosal melanoma (MucMlnm) of the H&N is a relatively uncommon malignancy that can occur in the oral cavity, nasal fossa, or paranasal sinuses (PNS). No level-1 evidence practice guideline likely exists due to its rarity (e.g., see Mendenhall et al., PMID 16317276, López et al., PMID 25242350). Our ancient review seemed to indicate that MucMlnm often progresses from local, regional to distant dissemination in a stepwise fashion (i.e., Halstead behavior) rather than being systemic at presentation (i.e., Fisher hy...