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What do you do for patients who have received accidental extra dosages of long-acting injectable antipsychotics?

3 Answers
Mednet Member
Mednet Member
Psychiatry · Medical College of Georgia
Answered on

Close monitoring, any EPS, one repeat EKG in a few days, reporting this to the family so that they are aware of the patient getting an extra dose, and cutting down or stopping any oral anti-psychotics to mitigate risk are some of the things I would do. There is no clear protocol on this, unfortunate...

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Psychiatry · Bassem Krayem, MD, PLLC
Answered on

It depends on what kind of long-acting injection. Most antipsychotics, except Zyprexa Relprevv, would only require close monitoring for side effects (like dystonia, muscle twitches, and muscle spasms). I would encourage getting an EKG to check for any QTc prolongation. If there are any signs of side...

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Psychiatry · Icahn School of Medicine at Mount Sinai/Mount Sinai Hospital
Answered on

In addition, the patient needs to be made aware of what side effects may occur, and perhaps a guardian or parent or group home, so that they can receive appropriate follow-up to address symptom relief.

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