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What dose constraints do you use when treating gastric MALT or DLBCL with radiation therapy?

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Mednet Member
Mednet Member
Radiation Oncology · Duke University Medical Center

Treatment of the entire stomach is recommended for gastric MALT lymphoma. A dose of 24-30 Gy is recommended, generally in 1.5 Gy fractions to limit acute toxicity. I am starting to utilize 24 Gy more frequently though, most studies have used 30 Gy. Gastric MALT tends to be multifocal, is not well vi...

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Mednet Member
Mednet Member
Radiation Oncology · Duke University Medical Center

Agree with Dr. @Dr. First Last's answer but would add the following comments:

  1. Lymphomas are one of the few malignancies for which randomized dose/response data are available. For indolent histologies, including gastric malt, 24 Gy is equivalent to larger doses, and superior to 4 Gy. There is no est...

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