What first line therapy would you give a premenopausal patient with HER-2 positive and ER positive metastatic breast cancer with visceral organ involvement?
Add OFS with endocrine therapy plus Taxane-HP combo? What taxane is preferred?
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What first line therapy would you give a premenopausal patient with ER+ HER2+ metastatic breast cancer with visceral organ involvement?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · Duke University
Answered on
This is a very good question. In the recently published SYSUCC-002 trial, trastuzumab plus endocrine therapy (ET) was not inferior to trastuzumab plus chemotherapy (CT) as first-line therapy for hormone receptor positive, HER2 positive, metastatic breast cancer. In this trial, 30% of patients were p...
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