What has been your experience with alternative injection sites to the abdomen for improving pain/tolerability with buprenorphine extended release?  

Injection site reactions (ISRs) are among the most commonly reported adverse effects of Sublocade. While rotating injection sites in the abdomen can help reduce these reactions, proper injection technique, patient education, monitoring, and timely management are equally important. Recently, the FDA ...

I agree with Dr. @Tang's comments about 1) rotating injection sites on the abdomen, 2) considering alternate sites per the new package insert, and 3) pretreating with lidocaine. In addition, I would recommend considering Brixadi, which has a smaller gauge needle (23G as opposed to a thicker 19G for ...