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What has been your experience with alternative injection sites to the abdomen for improving pain/tolerability with buprenorphine extended release?

2 Answers
Mednet Member
Mednet Member
Psychiatry · Massachusetts General Hospital

I agree with Dr. @Dr. First Last's comments about 1) rotating injection sites on the abdomen, 2) considering alternate sites per the new package insert, and 3) pretreating with lidocaine. In addition, I would recommend considering Brixadi, which has a smaller gauge needle (23G as opposed to a thicke...

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Mednet Member
Mednet Member
Psychiatry · Emory University School of Medicine

Injection site reactions (ISRs) are among the most commonly reported adverse effects of Sublocade. While rotating injection sites in the abdomen can help reduce these reactions, proper injection technique, patient education, monitoring, and timely management are equally important. Recently, the FDA ...

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