What has been your experience with CP250 vs. CP350 in terms of ease of implantation, post-operative course, and efficacy in IOP lowering?

We did look at this in our study from Wills (Shalaby et al., PMID 38158079) and did not find a difference in IOP control or medication use between CP250 or CP350. However, the CP350 cohort was small and this was a retrospective study. Similar findings have been published earlier regarding the BGI 250 vs BGI 350. I rarely implant CP350s and use mostly CP250s for most of my patients. I sometimes opt for a CP350 in a younger patient, but this is not evidence-based. The CP250 is somewhat easier to implant, as isolating the rectus muscles is not necessary, but the CP350 is not difficult once you get the hang of it. In my experience, the post-op course between the 2 shunts is similar.