What imaging workup should be completed in patients with a detectable PSA following prostatectomy?

The imaging work-up of recurrent prostate cancer is a topic of considerable interest. Our approach at UCLA has been to recommend, at the very least, a multiparametric MRI to evaluate for locoregional recurrence, and we regularly recommend a technetium bone scan as well. That being stated, we have be...

Although it is important to rule out distant disease in the setting of a rising PSA, the diagnostic yield of imaging tends to be low unless the absolute PSA is high or the PSA velocity is high or the doubling time is very low.

For bone scans, in a study of over a 120 patients, the yield of positive s...