What is a reasonable amount of ventricular arrhythmia burden on outpatient remote monitoring that would prompt consideration for VT ablation in patients with normal LV function and mild symptoms? 

The concern in this circumstance is the risk of the patient developing a PVC-meditated cardiomyopathy. It is clear that a subset of patients with a high burden of PVCs can be at risk for the development of left ventricular dysfunction. We also have data to show that reduction in the PVC burden for those patients (through ablation or antiarrhythmic drugs) is associated with improvement in the left ventricular function. It is not quite clear why some patients are susceptible to PVC-mediated cardiomyopathies and others are not and it is an active area of research.

Various studies have suggested different burdens that are associated with risk. Many of us begin to consider the risk when the PVC burden on Holter monitor is >10% with burdens >20% ...