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What is the best management of a lacrimal gland MALToma?

When radiation therapy is utilized, what should the radiation therapy treatment fields include and what imaging studies should be completed to assist with the RT plan and management? Should an EGD be completed to rule out gastric MALT lympoma? Is there a role for doxycycline antibiotic therapy prior to RT? When radiation therapy is used, what is the best radiation modality, electron therapy with placement of an eye shield, or photons with bolus? What is the risk of cataract formation or dry eye with radiation therapy treatment?
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

Ocular MALT can occur in the conjunctiva, lacrimal gland or retroorbital tissue. Although chlamydia can cause this, treatment with antibiotics without documenting infection has not been reported to have a significant response rate. Even in patients who test positive for DNA, I have seen mixed respon...

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