What is the best treatment dose and fractionation for WBRT in a patient who has numerous brain mets and previously received PCI with 25Gy/10fx for small cell lung cancer?
1 Answer
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
Based on re-irradiation series for whole brain available in literature (Value of whole brain re-irradiation for brain metastases--single centre experience. , Re-irradiation in the treatment of patients with cerebral metastases of solid tumors: retrospective analysis. ), reasonable palliation (improvement in neurological symptoms) is achieved with 20 Gy at 1.8 to 2 Gy per fractions and that's what we have been using in this scenario.
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