What is the best treatment for treatment resistant restless leg syndrome?

In general, when a condition is considered “treatment resistant”, it is useful to reconsider the diagnosis, assess the quality of the patient-doctor relationship, identify potential sources of treatment resistance, and identify multiple non-pharmacological approaches to addressing symptoms.

It can take time to respond. I’ll get a good dietary history and screen for eating disorders as well as overtraining. I usually bridge them with gabapentin while repleting iron. For malnourished patients, I’ll counsel them about eating a whole-food diet. Often, I’m recommending MVI and magnesium as ...