What is the best way to manage low systolic blood pressures on clozapine when the patient has failed multiple other antipsychotic trials?
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Do you use fludrocortisone to treat orthostatic hypotension secondary to clozapine?
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1 Answer
Mednet MemberInvited Expert
Psychiatry · University of Colorado
Answered on · Updated on
Orthostatic hypotension is considered a common side effect during clozapine titration, specifically due to its alpha-1 receptor antagonism. This effect is most commonly seen when initiating clozapine or with dose increases.
General initial strategies to address this side effect include reevaluating t...
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