What is the maximum dose that you would give to residual unresectable gross disease in the axilla in the setting of recurrent breast cancer s/p ALND?
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3 Answers
Mednet Member
Radiation Oncology · Baylor College of Medicine Department of Radiation Oncology
The FAST-Forward boost trial will be informative here, and I would recommend reading the protocol, because one can consider using the standard arm now, which is 40 Gy to the breast (and nodes, when RNI is indicated), and a 48 Gy boost, all in 15 fractions. This dose is recognizable as the breast boo...
Mednet Member
Radiation Oncology · UNC School of Medicine
Good question. For both supraclavicular and axillary gross nodes, the issues are quite similar; i.e., the brachial plexus makes it challenging to give a high enough dose to control gross disease. A few thoughts:
- For gross disease, it is always good to consider adding concurrent chemo as a sensitize...