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What is the most appropriate adjuvant chemotherapy regimen for pre-menopausal, pT1bN0, TNBC?

Would you forego anthracycline?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida
Answered on

In my opinion for T1bN0 TNBC tumors TCx4 is sufficient. In the ABC trials the absolute difference in N0 TNBC between the TCx6 and TaxAC arms was only 2.5%. This included larger tumors over 1 cm. A retrospective study in 1151 TNBC T1cN0 patients found a benefit for adjuvant chemotherapy in T1c patien...

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